Cell Biology Antibodies 13

MAP4K2 Rabbit Polyclonal Antibody (CAB17524)

(No reviews yet) Write a Review
SKU:
CAB17524
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
GCK, BL44, RAB8IP, MAP4K2
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

MAP4K2 Antibody (CAB17524)

The MAP4K2 Antibody (CAB17524) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody has been extensively validated for use in Western blot applications and is highly reactive with human samples, ensuring reliable and accurate results.MAP4K2, also known as mitogen-activated protein kinase kinase kinase kinase 2, is a critical regulator of various cellular processes, including cell growth, proliferation, and survival. Dysregulation of MAP4K2 activity has been implicated in several diseases, including cancer, inflammatory disorders, and autoimmune conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MAP4K2 Antibody
SKU:CAB17524
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:WAHD LPGL FEQR RLQQ QVPL SIPT NRLT QRII PRRF ALST KIPD TKGC LQCR VVRN PYTG ATFL LAAL PTSL LLLQ WYEP LQKF LLLK NFSS PLPS PAGM LEPL VLDG KELP QVCV GAEG PEGP GCRV LFHV LPLE AGLT PDIL IPPE GIPG SAQQ VIQV DRDT ILVS FERC VRIV NMQG EPTA TLAP ELTF DFPI ETVV CLQD SVLA FWSH GMQG RSLD TNEV TQEI TDET RIFR VLGA HRDI ILES IPTD NPEA HSNL YILT GHQS TY
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GCK, BL44, RAB8IP, MAP4K2
Positive Sample:U-87MG, A-549, C6, Raji, HeLa, Mouse lung
Cellular Localization:Basolateral Plasma Membrane, Cytoplasm.
Calculated MW:92kDa
Observed MW:110kDa

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID5871
RRIDAB_2770272
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MAP4K2 Rabbit pAb (CAB17524) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
View AllClose

0 Reviews

View AllClose

Related Products