Cell Biology Antibodies 4

MAN1A2 Rabbit Polyclonal Antibody (CAB14271)

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SKU:
CAB14271
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
MAN1B, MAN1A2
Research Use:
Cell Biology
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Description

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MAN1A2 Antibody (CAB14271)

The MAN1A2 Antibody (CAB14271) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.MAN1A2, a key enzyme in the glycosylation pathway, plays a crucial role in the quality control of glycoprotein folding and assembly in the endoplasmic reticulum. Dysregulation of MAN1A2 has been implicated in various diseases, making it a target of interest for researchers studying protein glycosylation disorders, cancer, and neurodegenerative diseases.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:MAN1A2 Antibody
SKU:CAB14271
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SSKH KRFD LGLE DVLI PHVD AGKG AKNP GVFL IHGP DEHR HREE EERL RNKI RADH EKAL EEAK EKLR KSRE EIRA EIQT EKNK VVQE MKIK ENKP LPPV PIPN LVGI RGGD PEDN DIRE K
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MAN1B, MAN1A2
Positive Sample:LO2, A-549, Mouse brain, Mouse liver
Cellular Localization:Golgi Apparatus Membrane, Single-Pass Type Ii Membrane Protein.
Calculated MW:73kDa
Observed MW:73kDa

Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.

Purification MethodAffinity purification
Gene ID10905
RRIDAB_2761134
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MAN1A2 Rabbit pAb (CAB14271) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon carcinoma using MAN1A2 Rabbit pAb (CAB14271) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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