Signal Transduction Antibodies 3

KCND3 Rabbit Polyclonal Antibody (CAB6927)

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SKU:
CAB6927
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVB, KCND3
Research Use:
Signal Transduction
Frequently bought together:

Description

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KCND3 Antibody (CAB6927)

The KCND3 Antibody (CAB6927) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting KCND3 in human samples, making it an excellent choice for Western blot applications.By targeting the KCND3 protein, this antibody allows for the precise detection and analysis of potassium channel activity in various cell types, providing valuable insights into the role of KCND3 in cellular function and disease processes.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:KCND3 Antibody
SKU:CAB6927
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MESS MQNY PSTR SPSL SSHP GLTT TCCS RRSK KTTH LPNS NLPA TRLR SMQE LSTI HIQG SEQP SLTT SRSS LNLK ADDG LRPN CKTS QITT AIIS IPTP PALT PEGE SRPP PASP GPNT NIPS IASN VVKV SAL
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:100 - 1:500
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVB, KCND3
Positive Sample:A-549, SH-SY5Y, Mouse heart, Rat heart
Cellular Localization:Cell Membrane, Cell Projection, Membrane, Multi-Pass Membrane Protein, Dendrite, Sarcolemma.
Calculated MW:73kDa
Observed MW:73kDa

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Purification MethodAffinity purification
Gene ID3752
RRIDAB_2767486
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using KCND3 Rabbit pAb (CAB6927) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat heart using KCND3 Rabbit pAb (CAB6927) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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