Epigenetics & Nuclear Signaling Antibodies 3

KAT6B Rabbit Polyclonal Antibody (CAB17116)

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SKU:
CAB17116
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf, KAT6B
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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KAT6B Antibody (CAB17116)

The KAT6B Antibody (CAB17116) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the KAT6B protein, researchers can easily detect and analyze its expression in various cell types, making it an essential component for studies in epigenetics and cancer research.KAT6B, also known as MYST4, plays a crucial role in controlling gene expression through histone acetylation, impacting various cellular processes such as cell differentiation and proliferation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:KAT6B Antibody
SKU:CAB17116
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:DLDV FKQA QELS WEKI ECES GVED CGRY PSVI EFGK YEIQ TWYS SPYP QEYA RLPK LYLC EFCL KYMK SKNI LLRH SKKC GWFH PPAN EIYR RKDL SVFE V
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf, KAT6B
Positive Sample:293T, HeLa, OVCAR3, Mouse heart
Cellular Localization:Nucleoplasm, Nucleus.
Calculated MW:231kDa
Observed MW:280kDa

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID23522
RRIDAB_2770037
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using KAT6B Rabbit pAb (CAB17116) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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