Cell Biology Antibodies 13

ITPKA Rabbit Polyclonal Antibody (CAB17503)

(No reviews yet) Write a Review
SKU:
CAB17503
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Mouse, Rat
Synonyms:
IP3KA, IP3-3KA, ITPKA
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

ITPKA Antibody (CAB17503)

The ITPKA Antibody (CAB17503) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. It binds specifically to the ITPKA protein, allowing for accurate detection and analysis in a variety of cell types.ITPKA is known to play a critical role in regulating cellular processes such as cell proliferation, differentiation, and apoptosis. Dysregulation of ITPKA has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:ITPKA Antibody
SKU:CAB17503
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LLSD SESR SRGN VQLE AGED VGQK NHWQ KIRT MVNL PVIS PFKK RYAW VQLA GHTG SFKA AGTS GLIL KRCS EPER YCLA RLMA DALR GCVP AFHG VVER DGES YLQL QDLL DGFD GPCV LDCK MGVR TYLE EELT KARE RPKL RKDM YKKM LAVD PEAP TEEE HAQR AVTK PRYM QWRE GISS STTL GFRI EGIK KADG SCST DFKT TRSR EQVL RVFE EFVQ GDEE VLRR YLNR LQQI RDTL EVSE FFRR HEVI GSSL LFVH DHCH RAGV WLID FGKT TPLP DGQI LDHR RPWE EGNR EDGY LLGL DNLI GILA SLAE R
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:IP3KA, IP3-3KA, ITPKA
Positive Sample:Mouse brain, Rat brain
Cellular Localization:Cytoplasm, Cytoskeleton, Cytosol, Dendritic Spine, Glutamatergic Synapse, Nucleus, Postsynaptic Actin Cytoskeleton.
Calculated MW:51kDa
Observed MW:55kDa

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Purification MethodAffinity purification
Gene ID3706
RRIDAB_2770017
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ITPKA Rabbit pAb (CAB17503) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
View AllClose

0 Reviews

View AllClose

Related Products