Immunology Antibodies 2

IKKbeta Rabbit Polyclonal Antibody (CAB2087)

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SKU:
CAB2087
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta, IKKβ
Research Use:
Immunology
Frequently bought together:

Description

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IKKbeta Antibody (CAB2087)

The IKKbeta Antibody (CAB2087) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through immunization of rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By specifically binding to the IKBKB protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in immunology and cancer research.IKBKB, also known as inhibitor of nuclear factor kappa-B kinase subunit beta, plays a crucial role in the activation of the NF-kappa-B signaling pathway, which is involved in various cellular processes such as inflammation, immune responses, and cell survival.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:IKKbeta Antibody
SKU:CAB2087
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:QISP RPQP ESVS CILQ EPKR NLAF FQLR KVWG QVWH SIQT LKED CNRL QQGQ RAAM MNLL RNNS CLSK MKNS MASM SQQL KAKL DFFK TSIQ IDLE KYSE QTEF GITS DKLL LAWR EMEQ AVEL CGRE NEVK LLVE RMMA LQTD IVDL QRSP MGRK QGGT LDDL EEQA RELY RRLR EKPR DQRT EGDS QEMV RLLL QAIQ SFEK KVRV IYTQ LSKT VVCK QKAL ELLP KVEE VVSL MNED EKTV VRLQ EKRQ KELW NLLK IACS KVRG PV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:5000 - 1:25000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta, IKKβ
Positive Sample:293T
Cellular Localization:Cytoplasm, Membrane Raft, Nucleus.
Calculated MW:29-87kDa
Observed MW:87kDa

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

Purification MethodAffinity purification
Gene ID3551
RRIDAB_2764107
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and 293T cells transfected with IKKβ siRNA using IKKβ Rabbit pAb (CAB2087) at 1:5000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 20 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020) .Exposure time: 10 s.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using IKKβ Rabbit pAb (CAB2087) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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