Epigenetics & Nuclear Signaling Antibodies 3

IGF2BP2/IMP2 Rabbit Polyclonal Antibody (CAB1774)

(No reviews yet) Write a Review
SKU:
CAB1774
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
IMP2, IMP-2, VICKZ2, IGF2BP2/IMP2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

IGF2BP2/IMP2 Antibody (CAB1774)

The IGF2BP2/IMP2 Antibody (CAB1774) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.IGF2BP2, also known as insulin-like growth factor 2 mRNA-binding protein 2, plays a crucial role in post-transcriptional regulation of gene expression, particularly in the context of cell proliferation and differentiation.

This antibody is validated for use in WB, IF/ICC, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:IGF2BP2/IMP2 Antibody
SKU:CAB1774
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TVEA CASA EIEI MKKL REAF ENDM LAVN QQAN LIPG LNLS ALGI FSTG LSVL SPPA GPRG APPA APYH PFTT HSGY FSSL YPHH QFGP FPHH HSYP EQEI VNLF IPTQ AVGA IIGK KGAH IKQL ARFA GASI KIAP AEGP DVSE RMVI ITGP PEAQ FKAQ GRIF GKLK EENF FNPK EEVK LEAH IRVP SSTA GRVI GKGG KTVN ELQN LTSA EVIV PRDQ TPDE NEEV IVRI IGHF FASQ TAQR KIRE IVQQ VKQQ EQKY PQGV ASQR SK
Tested Applications:WB IF/ICC ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:100
IF-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:IMP2, IMP-2, VICKZ2, IGF2BP2/IMP2
Positive Sample:HT-29, BxPC-3, HeLa, Jurkat, NIH/3T3
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:66kDa
Observed MW:70kDa

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.

Purification MethodAffinity purification
Gene ID10644
RRIDAB_2763816
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using IGF2BP2/IMP2 Rabbit pAb (CAB1774) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunofluorescence analysis of U-2 OS cells using IGF2BP2/IMP2 Rabbit pAb (CAB1774) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products