Cell Death Antibodies 1

IFI16 Rabbit Polyclonal Antibody (CAB14002)

(No reviews yet) Write a Review
SKU:
CAB14002
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
PYHIN2, IFNGIP1, IFI16
Research Use:
Cell Death
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

IFI16 Antibody (CAB14002)

The IFI16 Antibody (CAB14002) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the IFI16 protein, this antibody facilitates the detection and analysis of IFI16 in various cell types.IFI16, a member of the interferon-inducible HIN-200 family of proteins, plays a key role in the detection of viral and bacterial DNA in the cytoplasm, triggering immune responses to combat infections.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:IFI16 Antibody
SKU:CAB14002
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MGKK YKNI VLLK GLEV INDY HFRM VKSL LSND LKLN LKMR EEYD KIQI ADLM EEKF RGDA GLGK LIKI FEDI PTLE DLAE TLKK EKLK VKGP ALSR KRKK EVDA TSPA PSTS STVK TEGA EATP GAQK RKKS TKEK AGPK GSKV SEEQ TQPP SPAG AGMS TAMG RSPS PKTS LSAP PNSS STEN PKTV AKCQ VTPR RNVL QKRP VIVK VLST TKPF EYET PEME KKIM FHAT VATQ TQFF HVKV LNTS LKEK FNGK KIII ISDY LEYD SLLE VNEE STVS EAGP NQTF EVPN KIIN RAKE
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PYHIN2, IFNGIP1, IFI16
Positive Sample:U-87MG, Daudi
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:88kDa
Observed MW:85-98kDa

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID3428
RRIDAB_2760856
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using IFI16 Rabbit pAb (CAB14002) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 0.5s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat liver using IFI16 Rabbit pAb (CAB14002) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse lung using IFI16 Rabbit pAb (CAB14002) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
View AllClose

0 Reviews

View AllClose

Related Products