Developmental Biology

HTR2B Rabbit Polyclonal Antibody (CAB5670)

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SKU:
CAB5670
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
5-HT2B, 5-HT-2B, 5-HT(2B), HTR2B
Research Use:
Developmental Biology
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Description

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HTR2B Antibody (CAB5670)

The HTR2B Antibody (CAB5670) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the HTR2B protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal choice for studies in neuroscience and pharmacology.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HTR2B Antibody
SKU:CAB5670
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LFNK TFRD AFGR YITC NYRA TKSV KTLR KRSS KIYF RNPM AENS KFFK KHGI RNGI NPAM YQSP MRLR SSTI QSSS IILL DTLL LTEN EGDK TEEQ VSYV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:1000 - 1:6000
IF/ICC1:50 - 1:500
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:5-HT2B, 5-HT-2B, 5-HT(2B), HTR2B
Positive Sample:Mouse liver, Rat liver
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Synapse, Synaptosome.
Calculated MW:54kDa
Observed MW:54kDa

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

Purification MethodAffinity purification
Gene ID3357
RRIDAB_2766430
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using HTR2B Rabbit pAb (CAB5670) at 1:3000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60 s.
Product ImageImmunofluorescence analysis of U2OS cells using HTR2B Rabbit pAb (CAB5670). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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