Cardiovascular Antibodies

HRG Rabbit Polyclonal Antibody (CAB8431)

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SKU:
CAB8431
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cardiovascular
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse, Rat
Synonyms:
HPRG, HRGP, THPH11, HRG
Research Use:
Cardiovascular
Frequently bought together:

Description

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HRG Antibody (CAB8431)

The HRG Antibody (CAB8431) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for reliable use in Western blot applications. By binding to the HRG protein, this antibody enables the detection and analysis of HRG expression in different cell types, making it an essential tool for studies in molecular biology, cell signaling, and cancer research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:HRG Antibody
SKU:CAB8431
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SPTD CSAV EPEA EKAL DLIN KRRR DGYL FQLL RIAD AHLD RVEN TTVY YLVL DVQE SDCS VLSR KYWN DCEP PDSR RPSE IVIG QCKV IATR HSHE SQDL RVID FNCT TSSV SSAL ANTK DSPV LIDF FEDT ERYR KQAN KALE KYKE ENDD FASF RVDR IERV ARVR GGEG TGYF VDFS VRNC PRHH FPRH PNVF GFCR ADLF YDVE ALDL ESPK NLVI NCEV FDPQ EHEN INGV PPHL G
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HPRG, HRGP, THPH11, HRG
Positive Sample:Mouse pancreas
Cellular Localization:Secreted.
Calculated MW:60kDa
Observed MW:80kDa

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Purification MethodAffinity purification
Gene ID3273
RRIDAB_2769843
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from mouse pancreas, using HRG Rabbit pAb (CAB8431) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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