Epigenetics & Nuclear Signaling Antibodies 1

HR Rabbit Polyclonal Antibody (CAB11996)

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SKU:
CAB11996
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
AU, MUHH, ALUNC, HYPT4, MUHH1, HSA277165, HR
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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HR Antibody (CAB11996)

The HR Antibody (CAB11996) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in Western blot applications. It binds specifically to the HR protein, enabling researchers to detect and analyze its presence in various cell types, making it an ideal tool for studies in immunology and cancer research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HR Antibody
SKU:CAB11996
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:SLGS KGFY YKDP SIPR LAKE PLAA AEPG LFGL NSGG HLQR AGEA ERPS LHQR DGEM GAGR QQNP CPLF LGQP DTVP WTSW PACP PGLV HTLG NVWA GPGD GNLG YQLG PPAT PRCP SPEP PVTQ RGCC SSYP PTKG GGLG PCGK CQEG LEGG ASGA SEPS EEVN KASG PRAC PPSH HTKL KKTW LTRH SEQF ECPR GCPE VEER PVAR LRAL KRAG SPEV QGAM GSPA PKRP PDPF PGTA EQGA GGWQ EVRD TSIG NKDV DSGQ HDEQ KGPQ DGQA SLQD P
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AU, MUHH, ALUNC, HYPT4, MUHH1, HSA277165, HR
Positive Sample:U-251MG, Mouse brain, Rat brain
Cellular Localization:Nucleus.
Calculated MW:127kDa
Observed MW:120kDa

This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID55806
RRIDAB_2758920
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using HR Rabbit pAb (CAB11996) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 40s.
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