Cell Biology Antibodies 6

HPS4 Rabbit Polyclonal Antibody (CAB16157)

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SKU:
CAB16157
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
LE, BLOC3S2, HPS4
Research Use:
Cell Biology
Frequently bought together:

Description

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HPS4 Antibody (CAB16157)

The HPS4 Antibody (CAB16157) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly reactive with human samples and is validated for use in Western blot applications. By binding specifically to the HPS4 protein, this antibody allows for detection and analysis in various cell types, making it ideal for studies in cell biology and lysosomal storage disorders.HPS4, a subunit of the biogenesis of lysosome-related organelles complex-3 (BLOC-3), plays a critical role in the formation and function of lysosome-related organelles.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HPS4 Antibody
SKU:CAB16157
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:FAFL HVPV PDGR APYC KASL SASS SLEP TPPE DTAI SSLR PPSA PEML TQHG AQEQ LEDH PGHS SQAP IPRA DPLP RRTR RPLL LPRL DPGQ RGNK LPTG EQGL DEDV DGVC ESHA APGL ECSS GSAN CQGA GPSA DGIS SRLT PAES CMGL VRMN LYTH CVKG LVLS LLAE EPLL GDSA AIEE VYHS SLAS LNGL EVHL KETL PRDE AAST SSTY NFTH YDRI QSLL MANL PQVA TPQD RRFL QAVS LMHS EFAQ LPAL YEMT VRNA STAV YACC NPIQ ETYF QQLA PAAR SSGF PNPQ DGAF SLSG KAKQ KLLK HGVN LL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:LE, BLOC3S2, HPS4
Positive Sample:U-87MG
Cellular Localization:Cytoplasm, Cytoplasmic Vesicle, Cytosol, Lysosome, Melanosome.
Calculated MW:77kDa
Observed MW:90kDa

This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID89781
RRIDAB_2763605
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from U-87MG cells, using HPS4 Rabbit pAb (CAB16157) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Product ImageImmunofluorescence analysis of C6 cells using HPS4 Rabbit pAb (CAB16157) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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