Epigenetics & Nuclear Signaling Antibodies 2

HMGA1 Rabbit Polyclonal Antibody (CAB1635)

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SKU:
CAB1635
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
HMG-R, HMGIY, HMGA1A, HMGA1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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HMGA1 Antibody (CAB1635)

The HMGA1 Antibody (CAB1635) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific and reactive in human samples, making it ideal for Western blot applications. By binding to HMGA1, this antibody facilitates the detection and analysis of the protein in a variety of cell types.HMGA1 is a key player in gene regulation and has been implicated in a wide range of diseases including cancer, diabetes, and obesity. Its ability to manipulate gene expression makes it a promising target for therapeutic interventions in these conditions.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:HMGA1 Antibody
SKU:CAB1635
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MSES SSKS SQPL ASKQ EKDG TEKR GRGR PRKQ PPVS PGTA LVGS QKEP SEVP TPKR PRGR PKGS KNKG AAKT RKTT TTPG RKPR GRPK KLEK EEEE GISQ
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HMG-R, HMGIY, HMGA1A, HMGA1
Positive Sample:293T
Cellular Localization:Chromosome, Nucleus.
Calculated MW:12kDa
Observed MW:18kDa

This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

Purification MethodAffinity purification
Gene ID3159
RRIDAB_2763693
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using HMGA1 Rabbit pAb (CAB1635) at 1:3000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human stomach using HMGA1 Rabbit pAb (CAB1635) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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