Signal Transduction Antibodies 2

HEY2 Rabbit Polyclonal Antibody (CAB15143)

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SKU:
CAB15143
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
GRL, CHF1, HRT2, HERP1, HESR2, bHLHb32, GRIDLOCK, HEY2
Research Use:
Signal Transduction
Frequently bought together:

Description

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HEY2 Antibody (CAB15143)

The HEY2 Antibody (CAB15143) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody is produced in rabbits and is highly reactive with human samples, making it ideal for use in various research applications.HEY2 is known to play a critical role in regulating gene expression and cell differentiation, particularly in cardiac development and neurogenesis. Dysregulation of HEY2 has been implicated in various diseases, making it a target of interest for researchers studying cardiovascular disorders, neurodevelopmental diseases, and cancer.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HEY2 Antibody
SKU:CAB15143
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:TIDV GSEN NYSG QSTS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GRL, CHF1, HRT2, HERP1, HESR2, bHLHb32, GRIDLOCK, HEY2
Positive Sample:HeLa, HepG2, SH-SY5Y, Rat lung, Rat testis
Cellular Localization:Nucleus.
Calculated MW:36kDa
Observed MW:36kDa

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Purification MethodAffinity purification
Gene ID23493
RRIDAB_2762030
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using HEY2 Rabbit pAb (CAB15143) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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