Signal Transduction Antibodies 3

HERC3 Rabbit Polyclonal Antibody (CAB8567)

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SKU:
CAB8567
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
HERC3
Research Use:
Signal Transduction
Frequently bought together:

Description

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HERC3 Antibody (CAB8567)

The HERC3 Antibody (CAB8567) is a high-quality antibody developed for reliable detection and analysis of target proteins. This high-quality antibody, generated in rabbits, demonstrates exceptional reactivity with HERC3 in human samples and has been rigorously validated for Western blot applications.HERC3 is a vital component of the ubiquitin-proteasome system, a key pathway for protein degradation within cells. Dysregulation of this system has been linked to various diseases, including cancer and neurodegenerative disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:HERC3 Antibody
SKU:CAB8567
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MLCW GYWS LGQP GIST NLQG IVAE PQVC GFIS DRSV KEVA CGGN HSVF LLED GEVY TCGL NTKG QLGH EREG NKPE QIGA LADQ HIIH VACG ESHS LALS DRGQ LFSW GAGS DGQL GLMT TEDS VAVP RLIQ KLNQ QTIL QVSC GNWH CLAL AADG QFFT WGKN SHGQ LGLG KEFP SQAS PQRV RSLE GIPL AQVA AGGA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HERC3
Positive Sample:SH-SY5Y, U-87MG, A-431, Mouse lung, Mouse spinal cord
Cellular Localization:Cytoplasm, Cytoplasmic Vesicle.
Calculated MW:117kDa
Observed MW:117kDa

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification MethodAffinity purification
Gene ID8916
RRIDAB_2769763
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using HERC3 Rabbit pAb (CAB8567) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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