Signal Transduction Antibodies 3

HCN1 Polyclonal Antibody (CAB17279)

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SKU:
CAB17279
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
BCNG1, DEE24, HAC-2, BCNG-1, EIEE24, GEFSP10, HCN1
Frequently bought together:

Description

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HCN1 Polyclonal Antibody (CAB17279)

The HCN1 Polyclonal Antibody (CAB17279) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed in rabbits, exhibits high specificity and sensitivity for detecting HCN1 in human samples, making it ideal for use in Western blot applications.HCN1 plays a crucial role in regulating neuronal firing and rhythmic activity in the brain, making it a key target for understanding neurological disorders such as epilepsy, Parkinson's disease, and neuropathic pain.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HCN1 Polyclonal Antibody
SKU:CAB17279
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:PSLP HEVS TLIS RPHP TVGE SLAS IPQP VTAV PGTG LQAG GRST VPQR VTLF RQMS SGAI PPNR GVPP APPP PAAA LPRE SSSV LNTD PDAE KPRF ASNL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BCNG1, DEE24, HAC-2, BCNG-1, EIEE24, GEFSP10, HCN1
Positive Sample:SH-SY5Y, Neuro-2a, Mouse brain, Rat brain
Cellular Localization:Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:99kDa
Observed MW:99kDa

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes.

Purification MethodAffinity purification
Gene ID348980
RRIDAB_2769747
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using HCN1 Rabbit pAb (CAB17279) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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