Cell Biology Antibodies 10

GLUD2 Rabbit Polyclonal Antibody (CAB6604)

(No reviews yet) Write a Review
SKU:
CAB6604
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
GDH2, GLUDP1, GLUD2
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GLUD2 Antibody (CAB6604)

The GLUD2 Antibody (CAB6604) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for Western blot applications.GLUD2 is known to play a crucial role in the metabolism of glutamate, a key neurotransmitter in the central nervous system. Dysregulation of GLUD2 activity has been implicated in various neurological disorders, making it a target of interest for researchers studying conditions such as epilepsy, Parkinson's disease, and Alzheimer's disease.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GLUD2 Antibody
SKU:CAB6604
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:YLHR FGAK CIAV GESD GSIW NPDG IDPK ELED FKLQ HGSI LGFP KAKP YEGS ILEV DCDI LIPA ATEK QLTK SNAP RVKA KIIA EGAN GPTT PEAD KIFL ERNI LVIP DLYL NAGG VTVS YFEW LKNL NHVS YGRL TFKY ERDS NYHL LLSV QESL ERKF GKHG GTIP IVPT AEFQ DSIS GASE KDIV HSAL AYTM ERSA RQIM HTAM KYNL GLDL RTAA YVNA IEKV FKVY SEAG VTFT
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GDH2, GLUDP1, GLUD2
Positive Sample:HepG2, A-431, U-937
Cellular Localization:Mitochondrion Matrix.
Calculated MW:61kDa
Observed MW:52kDa

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Purification MethodAffinity purification
Gene ID2747
RRIDAB_2767195
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using GLUD2 Rabbit pAb (CAB6604) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon carcinoma using GLUD2 Rabbit pAb (CAB6604) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of HepG2 cells using GLUD2 Rabbit pAb (CAB6604) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using GLUD2 Rabbit pAb (CAB6604) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products