Epigenetics & Nuclear Signaling Antibodies 1

GEN1 Rabbit Polyclonal Antibody (CAB10001)

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SKU:
CAB10001
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
Gen, GEN1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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GEN1 Antibody (CAB10001)

The GEN1 Antibody (CAB10001) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, boasts high reactivity with human samples and is ideal for use in Western blot applications. By specifically binding to the CD300A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a valuable asset for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by regulating inflammation and suppressing allergic responses.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:GEN1 Antibody
SKU:CAB10001
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LQDL PLKE RIFT KLSY PQDN LQPD VNLK TLSI LSVK ESCI ANSG SDCT SHLS KDLP GIPL QNES RDSK ILKG DQLL QEDY KVNT SVPY SVSN TVVK TCNV RPPN TALD HSRK VDMQ TTRK ILMK KSVC LDRH SSDE QSAP VFGK AKYT TQRM KHSS QKHN SSHF KESG HNKL SSPK IHIK ETEQ CVRS YETA ENEE SCFP DSTK SSLS SLQC HKKE NNSG TCLD SPLP LRQR LKLR FQST
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Gen, GEN1
Positive Sample:H460, MCF-7, Mouse thymus, Mouse spleen
Cellular Localization:Nucleus.
Calculated MW:103kDa
Observed MW:103kDa

This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID348654
RRIDAB_2757521
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using GEN1 Rabbit pAb (CAB10001) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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