Cell Biology Antibodies 13

GEMIN5 Rabbit Polyclonal Antibody (CAB17125)

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SKU:
CAB17125
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
NEDCAM, GEMIN-5, GEMIN5
Research Use:
Cell Biology
Frequently bought together:

Description

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GEMIN5 Antibody (CAB17125)

The GEMIN5 Antibody (CAB17125) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the Gemin5 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in RNA biology, gene regulation, and developmental biology.Gemin5, a crucial component of the spliceosomal complex, plays a vital role in RNA splicing and transport, as well as in the regulation of gene expression.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GEMIN5 Antibody
SKU:CAB17125
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:RTPV KLES IDGN EEES MKEN SGPV ENGV SDQE GEEQ AREP ELPC GLAP AVSR EPVI CTPV SSGF EKSK VTIN NKVI LLKK EPPK EKPE TLIK KRKA RSLL PLST SLDH RSKE ELHQ DCLV LATA KHSR ELNE DVSA DVEE RFHL GLFT DRAT LYRM IDIE GKGH LENG HPEL FHQL MLWK GDLK GVLQ TAAE RGEL TDNL V
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NEDCAM, GEMIN-5, GEMIN5
Positive Sample:HeLa
Cellular Localization:Cytoplasm, Cytosol, Gemini Of Coiled Bodies, Nuclear Body, Nucleoplasm, Nucleus, Smn-Sm Protein Complex.
Calculated MW:169kDa
Observed MW:180kDa

This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification MethodAffinity purification
Gene ID25929
RRIDAB_2769592
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using GEMIN5 Rabbit pAb (CAB17125) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat kidney using GEMIN5 Rabbit pAb (CAB17125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human placenta using GEMIN5 Rabbit pAb (CAB17125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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