Epigenetics & Nuclear Signaling Antibodies 4

GABPA Rabbit Polyclonal Antibody (CAB8419)

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SKU:
CAB8419
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Applications:
IF
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07, GABPA
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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GABPA Antibody (CAB8419)

The GABPA Antibody (CAB8419) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications, allowing for the detection and analysis of Gabpa protein levels in various cell types.Gabpa, also known as GA-binding protein alpha chain, is involved in regulating gene expression related to cell growth, differentiation, and apoptosis. Its function in controlling transcription makes it a key player in processes such as immune response, cell proliferation, and development.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GABPA Antibody
SKU:CAB8419
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MTKR EAEE LIEI EIDG TEKA ECTE ESIV EQTY APAE CVSQ AIDI NEPI GNLK KLLE PRLQ CSLD AHEI CLQD IQLD PERS LFDQ GVKT DGTV QLSV QVIS YQGI EPKL NILE IVKP ADTV EVVI DPDA HHAE SEAH LVEE AQVI TLDG TKHI TTIS DETS EQVT RWAA ALEG YRKE QERL GIPY DPIQ WSTD QVLH WVVW VMKE FSMT DIDL TTLN ISGR ELCS LNQE DFFQ RVPR GEIL WSHL ELLR KYVL ASQE QQMN
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07, GABPA
Positive Sample:SW480, HT-1080, Mouse heart, Mouse kidney
Cellular Localization:Nucleus.
Calculated MW:51kDa
Observed MW:56kDa

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

Purification MethodAffinity purification
Gene ID2551
RRIDAB_2769557
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using GABPA Rabbit pAb (CAB8419) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human uterine cancer using GABPA Rabbit pAb (CAB8419) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunofluorescence analysis of HeLa cells using GABPA Rabbit pAb (CAB8419) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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