Cell Biology Antibodies 2

FUCA2 Rabbit Polyclonal Antibody (CAB12211)

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SKU:
CAB12211
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
dJ20N2.5, FUCA2
Research Use:
Cell Biology
Frequently bought together:

Description

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FUCA2 Antibody (CAB12211)

The FUCA2 Antibody (CAB12211) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting FUCA2 in human samples, particularly in Western blot applications.FUCA2 plays a crucial role in the breakdown of complex carbohydrates, specifically in the degradation of fucosylated glycoconjugates. Dysregulation of FUCA2 activity has been implicated in various metabolic disorders and diseases, making it a promising target for therapeutic interventions.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:FUCA2 Antibody
SKU:CAB12211
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ADIF QASG AKYI VLTS KHHE GFTL WGSE YSWN WNAI DEGP KRDI VKEL EVAI RNRT DLRF GLYY SLFE WFHP LFLE DESS SFHK RQFP VSKT LPEL YELV NNYQ PEVL WSDG DGGA PDQY WNST GFLA WLYN ESPV RGTV VTND RWGA GSIC KHGG FYTC SDRY NPGH LLPH KWEN CMTI DKLS WGYR REAG ISDY LTIE ELVK QLVE TVSC GGNL LMNI GPTL DGTI SVVF EERL RQMG SWLK VNGE AIYE THTW RSQN DTVT PDVW YTSK PKEK LVYA IFLK WPTS GQLF LGHP KAIL GATE VKLL GHGQ PLNW ISLE QNGI MVEL PQLT IHQM PCKW GWAL ALTN VI
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:dJ20N2.5, FUCA2
Positive Sample:LO2, Mouse kidney, Mouse heart, Mouse stomach, Rat kidney, Rat heart
Cellular Localization:Secreted.
Calculated MW:54kDa
Observed MW:45kDa

This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells.

Purification MethodAffinity purification
Gene ID2519
RRIDAB_2759092
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using FUCA2 Rabbit pAb (CAB12211) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human liver cancer using FUCA2 Rabbit pAb (CAB12211) at dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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