Cell Biology Antibodies 17
Anti-Flotillin 1 Antibody (CAB3023)
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- SKU:
- CAB3023
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Flotillin 1 Antibody |
| Antibody SKU: | CAB3023 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Flotillin 1 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse brain, Mouse heart, Rat brain, Rat heart, HeLa, A-549 |
| Immunogen: | A synthesized peptide derived from human Flotillin 1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10211 |
| Uniprot: | O75955 |
| Cellular Location: | |
| Calculated MW: | 48kDa |
| Observed MW: | 47KDa |
| Synonyms: | |
| Background: | This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Protein Function: | FLOT1: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECM29. Belongs to the band 7/mec-2 family. Flotillin subfamily. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: signalosome; focal adhesion; membrane; lysosomal membrane; integral to membrane; melanosome; microtubule organizing center; caveola; flotillin complex; sarcolemma; endosome; lipid raft Molecular Function:ionotropic glutamate receptor binding; protein binding; protease binding Biological Process: extracellular matrix disassembly; axonogenesis; regulation of Rho protein signal transduction |
| NCBI Summary: | Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75955 |
| NCBI GenInfo Identifier: | 26006960 |
| NCBI Gene ID: | 10211 |
| NCBI Accession: | O75955.3 |
| UniProt Secondary Accession: | O75955,Q969J8, Q9UHW1, Q9UNV8, B4DVY7, |
| UniProt Related Accession: | O75955 |
| Molecular Weight: | 42,080 Da |
| NCBI Full Name: | Flotillin-1 |
| NCBI Synonym Full Names: | flotillin 1 |
| NCBI Official Symbol: | FLOT1 |
| NCBI Protein Information: | flotillin-1; integral membrane component of caveolae |
| UniProt Protein Name: | Flotillin-1 |
| Protein Family: | Flotillin-like protein |
| UniProt Gene Name: | FLOT1 |
| UniProt Entry Name: | FLOT1_HUMAN |
 | Western blot - Flotillin 1 Rabbit mAb (CAB3023) |
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