Cell Biology Antibodies 6

FIG4 Rabbit Polyclonal Antibody (CAB15372)

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SKU:
CAB15372
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
BOP, YVS, BTOP, SAC3, ALS11, CMT4J, KIAA0274, dJ249I4.1, FIG4
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

FIG4 Antibody (CAB15372)

The FIG4 Antibody (CAB15372) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human Fig4 protein, making it an ideal choice for Western blot applications.Fig4, a phosphoinositide phosphatase, is involved in the regulation of membrane trafficking and has been implicated in various physiological processes, such as autophagy and lysosomal function.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:FIG4 Antibody
SKU:CAB15372
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:WELP TDFY LHHK NTMR LLPT RRSY TYWW TPEV IKHL PLPY DEVI CAVN LKKL IVKK FHKY EEEI DIHN EFFR PYEL SSFD DTFC LAMT SSAR DFMP KTVG IDPS PFTV RKPD ETGK SVLG NKSN REEA VLQR KTAA SAPP PPSE EAVS SSSE DDSG TDRE EEGS VSQR STPV KMTD AGDS AKVT ENVV QPMK ELYG INLS DGLS EEDF SIYS RFVQ LGQS QHKQ DKNS QQPC SRCS DGVI KLTP ISAF SQDN IYEV QPPR VDRK STEI FQAH IQAS QGIM QPLG KEDS SMYR EYIR NRYL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:200 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BOP, YVS, BTOP, SAC3, ALS11, CMT4J, KIAA0274, dJ249I4.1, FIG4
Positive Sample:U-251MG, HT-29, Jukat, HeLa, Mouse liver, Mouse spleen
Cellular Localization:Endosome Membrane.
Calculated MW:104kDa
Observed MW:104kDa

The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

Purification MethodAffinity purification
Gene ID9896
RRIDAB_2762277
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using FIG4 Rabbit pAb (CAB15372) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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