Cell Biology Antibodies 13

FGFR1OP Rabbit Polyclonal Antibody (CAB17627)

(No reviews yet) Write a Review
SKU:
CAB17627
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Mouse, Rat
Synonyms:
FOP, FGFR1OP
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

FGFR1OP Antibody (CAB17627)

The FGFR1OP Antibody (CAB17627) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific for human samples and is suitable for use in various applications, including Western blot and immunohistochemistry.FGFR1 is a crucial component in cellular signaling pathways involved in development, tissue repair, and disease progression. Dysregulation of FGFR1 has been implicated in a variety of cancers, making it an attractive target for cancer research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:FGFR1OP Antibody
SKU:CAB17627
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAAT AAAV VAEE DTEL RDLL VQTL ENSG VLNR IKAE LRAA VFLA LEEQ EKVE NKTP LVNE SLKK FLNT KD
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:FOP, FGFR1OP
Positive Sample:Mouse kidney, Mouse brain
Cellular Localization:Cytoplasm, Centrosome, Cytoskeleton, Microtubule Organizing Center.
Calculated MW:43kDa
Observed MW:43kDa

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.

Purification MethodAffinity purification
Gene ID11116
RRIDAB_2769468
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using FGFR1OP Rabbit pAb (CAB17627) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products