Immunology Antibodies 2

FCN1 Rabbit Polyclonal Antibody (CAB6587)

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SKU:
CAB6587
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
FCNM, FCN1
Research Use:
Immunology
Frequently bought together:

Description

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FCN1 Antibody (CAB6587)

The FCN1 Antibody (CAB6587) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to ficolin-1, this antibody enables precise detection and analysis of the protein in various cell types.Ficolin-1 is a key player in innate immunity, functioning as a pattern recognition receptor that can identify and bind to pathogens, activating the immune response. Research into ficolin-1 is crucial for understanding how the innate immune system functions and responds to threats.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:FCN1 Antibody
SKU:CAB6587
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ADTC PEVK VVGL EGSD KLTI LRGC PGLP GAPG PKGE AGVI GERG ERGL PGAP GKAG PVGP KGDR GEKG MRGE KGDA GQSQ SCAT GPRN CKDL LDRG YFLS GWHT IYLP DCRP LTVL CDMD TDGG GWTV FQRR MDGS VDFY RDWA AYKQ GFGS QLGE FWLG NDNI HALT AQGS SELR VDLV DFEG NHQF AKYK SFKV ADEA EKYK LVLG AFVG GSAG NSLT GHNN NFFS TKDQ DNDV SSSN CAEK FQGA WWYA DCHA SNLN GLYL MGPH ESYA NGIN WSAA KGYK YSYK VSEM KVRP A
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:FCNM, FCN1
Positive Sample:U-937, U-251MG, HepG2, Mouse liver, Mouse heart, Rat liver
Cellular Localization:Cell Membrane, Extracellular Side, Peripheral Membrane Protein, Secreted.
Calculated MW:35kDa
Observed MW:38kDa

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

Purification MethodAffinity purification
Gene ID2219
RRIDAB_2767180
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using FCN1 Rabbit pAb (CAB6587) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
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