Cell Biology Antibodies 11

FCGR3B Rabbit Polyclonal Antibody (CAB7894)

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SKU:
CAB7894
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CD16, FCG3, CD16A, CD16b, FCGR3, CD16-I, FCGR3A, FCR-10, FCRIII, FCRIIIb, FCGR3B
Research Use:
Cell Biology
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Description

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FCGR3B Antibody (CAB7894)

The FCGR3B Antibody (CAB7894) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for Western blot applications. By binding to the FCGR3B protein, this antibody allows for precise detection and analysis in a variety of cell types, making it essential for studies in immunology and cancer research.FCGR3B, also known as CD16, is involved in the regulation of antibody-dependent cellular cytotoxicity (ADCC) and plays a crucial role in the immune system's ability to target and destroy infected or abnormal cells.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:FCGR3B Antibody
SKU:CAB7894
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MWQL LLPT ALLL LVSA GMRT EDLP KAVV FLEP QWYS VLEK DSVT LKCQ GAYS PEDN STQW FHNE NLIS SQAS SYFI DAAT VNDS GEYR CQTN LSTL SDPV QLEV HIGW LLLQ APRW VFKE EDPI HLRC HSWK NTAL HKVT YLQN GKDR KYFH HNSD FHIP KATL KDSG SYFC RGLV GSKN VSSE TVNI TITQ GLAV STIS SFSP PGYQ VSFC LVMV LLFA VDTG LYFS VKTN I
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CD16, FCG3, CD16A, CD16b, FCGR3, CD16-I, FCGR3A, FCR-10, FCRIII, FCRIIIb, FCGR3B
Positive Sample:Jurkat, Raji, U-937, THP-1, Mouse liver, Mouse spleen, Mouse thymus, Rat spleen
Cellular Localization:Cell Membrane, Gpi-Anchor, Lipid-Anchor, Secreted.
Calculated MW:26kDa
Observed MW:26kDa/46kDa

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Purification MethodAffinity purification
Gene ID2215
RRIDAB_2769443
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using FCGR3B Rabbit pAb (CAB7894) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.
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