Cell Biology Antibodies 1

EVPL Rabbit Polyclonal Antibody (CAB10215)

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SKU:
CAB10215
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
EVPK, EVPL
Research Use:
Cell Biology
Frequently bought together:

Description

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EVPL Antibody (CAB10215)

The EVPL Antibody (CAB10215) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various research applications, including immunohistochemistry and Western blotting.Envoplakin is a crucial component of desmosomes, cell structures that provide strength and stability to epithelial tissues. Dysregulation of envoplakin has been linked to skin disorders and diseases such as pemphigus, making it an important target for investigation in dermatology and skin biology research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:EVPL Antibody
SKU:CAB10215
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TKPS SSLS IGSI ISKS PLAS PAPQ STSF FSPS FSLG LGDD SFPI AGIY DTTT DNKC SIKT AVAK NMLD PITG QKLL EAQA ATGG IVDL LSRE RYSV HKAM ERGL IENT STQR LLNA QKAF TGIE DPVT KKRL SVGE AVQK GWMP RESV LPHL QVQH LTGG LIDP KRTG RIPI QQAL LSGM ISEE LAQL LQDE SSYE KDLT DPIS KERL SYKE AMGR CRKD PLSG LLLL PAAL EGYR CYRS ASPT VPRS LR
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EVPK, EVPL
Positive Sample:HeLa, Mouse lung, Rat lung
Cellular Localization:Cell Junction, Cornified Envelope, Cytoplasm, Cytoskeleton, Desmosome.
Calculated MW:232kDa
Observed MW:270kDa

This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.

Purification MethodAffinity purification
Gene ID2125
RRIDAB_2757738
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using EVPL Rabbit pAb (CAB10215) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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