The DLX5 Monoclonal Antibody (CAB5586) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for detecting DLX5 in human samples and has been validated for use in Western blot and immunohistochemistry applications.DLX5 plays a key role in regulating gene expression during development, particularly in the formation of bones and teeth. Dysregulation of DLX5 has been implicated in various diseases, including craniofacial abnormalities and certain cancers.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
DLX5 Monoclonal Antibody
SKU:
CAB5586
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC1994
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SHFM1, SHFM1D, DLX5
Positive Sample:
HeLa, 293T, U-87MG
Cellular Localization:
Nucleus.
Calculated MW:
32kDa
Observed MW:
32kDa
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
Purification Method
Affinity purification
Gene ID
1749
RRID
AB_2863511
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using DLX5 Rabbit mAb (CAB5586) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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