Cell Biology Antibodies 18

DEFA5 Rabbit Polyclonal Antibody (CAB18208)

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SKU:
CAB18208
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Synonyms:
DEF5, HD-5, DEFA5
Research Use:
Cell Biology
Frequently bought together:

Description

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DEFA5 Antibody (CAB18208)

The DEFA5 Antibody (CAB18208) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blot applications, enabling detection and analysis of DEFA5 in various cell types.DEFA5, also known as human alpha defensin 5, plays a crucial role in the host defense mechanism by targeting and killing pathogens such as bacteria and viruses.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:DEFA5 Antibody
SKU:CAB18208
Size:20μL, 100μL
Reactivity:Human
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ESLQ ERAD EATT QKQS GEDN QDLA ISFA GNGL SALR TSGS QARA TCYC RTGR CATR ESLS GVCE ISGR LYRL CCR
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DEF5, HD-5, DEFA5
Positive Sample:HCT116
Cellular Localization:Extracellular Region, Extracellular Space, Golgi Lumen, Transport Vesicle.
Calculated MW:10kDa
Observed MW:12kDa

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Purification MethodAffinity purification
Gene ID1670
RRIDAB_2861984
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from HCT116 cells, using DEFA5 Rabbit pAb (CAB18208) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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