Cell Death Antibodies 1

DDX47 Rabbit Polyclonal Antibody (CAB10359)

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SKU:
CAB10359
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
RRP3, E4-DBP, HQ0256, MSTP162, DDX47
Research Use:
Cell Death
Frequently bought together:

Description

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DDX47 Antibody (CAB10359)

The DDX47 Antibody (CAB10359) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.DDX47 is a member of the DEAD-box RNA helicase family and plays a vital role in various cellular processes, including RNA splicing, translation, and ribosome biogenesis. Dysregulation of DDX47 has been linked to diseases such as cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:DDX47 Antibody
SKU:CAB10359
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TEVD KILK VIPR DRKT FLFS ATMT KKVQ KLQR AALK NPVK CAVS SKYQ TVEK LQQY YIFI PSKF KDTY LVYI LNEL AGNS FMIF CSTC NNTQ RTAL LLRN LGFT AIPL HGQM SQSK RLGS LNKF KAKA RSIL LATD VASR GLDI PHVD VVVN FDIP THSK DYIH RVGR TARA GRSG KAIT FVTQ YDVE LFQR IEHL IGKK LPGF PTQD DEVM MLTE RVAE AQRF ARME LREH GEKK KRSR EDAG DNDD TEGA IGVR NKVA GGKM KKRK GR
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RRP3, E4-DBP, HQ0256, MSTP162, DDX47
Positive Sample:U-87MG, SKOV3, LO2, HeLa, Mouse testis, Mouse lung, Rat testis
Cellular Localization:Nucleus, Nucleolus.
Calculated MW:51kDa
Observed MW:50kDa

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID51202
RRIDAB_2757904
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DDX47 Rabbit pAb (CAB10359) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
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