ChIP Antibodies

DDX11 Rabbit Polyclonal Antibody (CAB7666)

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SKU:
CAB7666
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
CHL1, KRG2, WABS, CHLR1, DDX11
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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DDX11 Antibody (CAB7666)

The DDX11 Antibody (CAB7666) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the DDX11 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it perfect for studies in genetics, cancer research, and molecular biology.DDX11, also known as ChlR1 (Chl1-like protein 1), is essential for maintaining genomic stability and preventing the accumulation of genetic mutations that can lead to diseases like cancer.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:DDX11 Antibody
SKU:CAB7666
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MANE TQKV GAIH FPFP FTPY SIQE DFMA ELYR VLEA GKIG IFES PTGT GKSL SLIC GALS WLRD FEQK KREE EARL LETG TGPL HDEK DESL CLSS SCEG AAGT PRPA GEPA WVTQ FVQK KEER DLVD RLKA EQAR RKQR EERL QQLQ HRVQ LKYA AKRL RQEE EERE NLLR LSRE MLET GPEA ERLE QLES GEEE LVLA EYES DEEK KVAS RVDE DEDD
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CHL1, KRG2, WABS, CHLR1, DDX11
Positive Sample:HT-29, MCF7
Cellular Localization:Nucleus, Nucleolus.
Calculated MW:108kDa
Observed MW:108kDa

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Purification MethodAffinity purification
Gene ID1663
RRIDAB_2769130
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DDX11 Rabbit pAb (CAB7666) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 20s.
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