Epigenetics & Nuclear Signaling Antibodies 3

DDB2 Rabbit Polyclonal Antibody (CAB1848)

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SKU:
CAB1848
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
XPE, DDBB, UV-DDB2, DDB2
Research Use:
Epigenetics and Nuclear Signaling
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Description

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DDB2 Antibody (CAB1848)

The DDB2 Antibody (CAB1848) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the DDB2 protein, researchers can accurately detect and analyze its expression levels in various cell types.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:DDB2 Antibody
SKU:CAB1848
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAPK KRPE TQKT SEIV LRPR NKRS RSPL ELEP EAKK LCAK GSGP SRRC DSDC LWVG LAGP QILP PCRS IVRT LHQH KLGR ASWP SVQQ GLQQ SFLH TLDS YRIL QKAA PFDR RATS LAWH PTHP STVA VGSK GGDI MLWN FGIK DKPT FIKG IGAG GSIT GLKF NPLN TNQF YASS MEGT TRLQ DFKG NILR VFAS SDTI NIWF CSLD VSAS SRMV VTGD NVGN VILL NMDG KELW NLRM HKKK VTHV ALNP CCDW FLAT ASVD QTVK IWDL RQVR GKAS FLYS LPHR HPVN AACF SPDG ARLL TTDQ KSEI RVY
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:XPE, DDBB, UV-DDB2, DDB2
Positive Sample:Mouse liver, Rat liver
Cellular Localization:Nucleus.
Calculated MW:48kDa
Observed MW:48kDa

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID1643
RRIDAB_2763884
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DDB2 Rabbit pAb (CAB1848) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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