Epigenetics & Nuclear Signaling Antibodies 4

DCP2 Rabbit Polyclonal Antibody (CAB8282)

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SKU:
CAB8282
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Applications:
IF
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
NUDT20, DCP2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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DCP2 Antibody (CAB8282)

The DCP2 Antibody (CAB8282) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds specifically to the DCP2 protein, allowing for accurate detection and analysis in a variety of cell types.DCP2 is a key player in mRNA decapping, a critical step in the regulation of gene expression and RNA turnover. Dysregulation of DCP2 has been implicated in various disease processes, making it an important target for research in areas such as cancer, neurodegenerative disorders, and viral infections.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:DCP2 Antibody
SKU:CAB8282
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:METK RVEI PGSV LDDL CSRF ILHI PSEE RDNA IRVC FQIE LAHW FYLD FYMQ NTPG LPQC GIRD FAKA VFSH CPFL LPQG EDVE KVLD EWKE YKMG VPTY GAII LDET LENV LLVQ GYLA KSGW GFPK GKVN KEEA PHDC AARE VFEE TGFD IKDY ICKD DYIE LRIN DQLA RLYI IPGI PKDT KFNP KTRR EIRN IEWF SIEK LPCH RNDM TPKS KLGL APNK FFMA IPFI RPLR DWLS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NUDT20, DCP2
Positive Sample:K-562, 293T
Cellular Localization:Cytoplasm, Nucleus, P-Body.
Calculated MW:48kDa
Observed MW:44kDa

The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Purification MethodAffinity purification
Gene ID167227
RRIDAB_2769123
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using DCP2 Rabbit pAb (CAB8282) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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