Cell Biology Antibodies 5

DCN Rabbit Polyclonal Antibody (CAB15048)

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SKU:
CAB15048
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CSCD, PG40, PGII, PGS2, DSPG2, SLRR1B, DCN
Research Use:
Cell Biology
Frequently bought together:

Description

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DCN Antibody (CAB15048)

The DCN Antibody (CAB15048) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting and immunohistochemistry applications.DCN, also known as decorin, is known to interact with various growth factors and cell surface receptors, influencing processes such as cell proliferation, migration, and adhesion. Its involvement in modulating the activity of signaling pathways makes it a key player in tissue homeostasis and remodeling.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:DCN Antibody
SKU:CAB15048
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:DEAS GIGP EVPD DRDF EPSL GPVC PFRC QCHL RVVQ CSDL GLDK VPKD LPPD TTLL DLQN NKIT EIKD GDFK NLKN LHAL ILVN NKIS KVSP GAFT PLVK LERL YLSK NQLK ELPE KMPK TLQE LRAH ENEI TKVR KVTF NGLN QMIV IELG TNPL KSSG IENG AFQG MKKL SYIR IADT NITS IPQG LPPS LTEL HLDG NKIS RVDA ASLK GLNN LAKL GLSF NSIS AVDN GSLA NTPH LREL HLDN NKLT RVPG GLAE HKYI QVVY LHNN NISV VGSS DFCP PGHN TKKA SYSG VSLF SNPV QYWE IQPS TFRC VYVR SAIQ LGNY K
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CSCD, PG40, PGII, PGS2, DSPG2, SLRR1B, DCN
Positive Sample:HeLa, Mouse heart, Rat heart
Cellular Localization:Secreted, Extracellular Matrix, Extracellular Space.
Calculated MW:40kDa
Observed MW:45kDa/48kDa

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

Purification MethodAffinity purification
Gene ID1634
RRIDAB_2761929
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DCN Rabbit pAb (CAB15048) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
Product ImageWestern blot analysis of lysates from HeLa cells, using DCN Rabbit pAb (CAB15048) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human placenta using DCN Rabbit pAb (CAB15048) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human testis using DCN Rabbit pAb (CAB15048) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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