Cell Cycle Antibodies 1
Anti-CSNK1A1 Antibody (CAB16225)
- SKU:
- CAB16225
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-CSNK1A1 Antibody |
| Antibody SKU: | CAB16225 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CSNK1A1 (NP_001020276.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, HeLa, MCF7, PC-3, Mouse brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CSNK1A1 (NP_001020276.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LFNF CSRR FTMK TVLM LADQ MISR IEYV HTKN FIHR DIKP DNFL MGIG RHCN KCLE SPVG KRKR SMTV STSQ DPSF SGLN QLFL IDFG LAKK YRDN RTRQ H |
| Gene ID: | 1452 |
| Uniprot: | P48729 |
| Cellular Location: | Chromosome, Cytoplasm, Nucleus speckle, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center |
| Calculated MW: | 37kDa/38kDa/41kDa |
| Observed MW: | 38kDa |
| Synonyms: | CSNK1A1, CK1, CK1a, CKIa, HEL-S-77p, HLCDGP1, PRO2975 |
| Background: |
| UniProt Protein Function: | CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation. |
| UniProt Protein Details: | Protein type:Protein kinase, CK1; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 5q32 Cellular Component: beta-catenin destruction complex; centrosome; cytosol; keratin filament; membrane; mRNA cleavage and polyadenylation specificity factor complex; nuclear speck Molecular Function:kinase activity; protein binding; protein kinase activity; protein serine/threonine kinase activity Biological Process: cell surface receptor linked signal transduction; Golgi organization and biogenesis; intermediate filament cytoskeleton organization and biogenesis; peptidyl-serine phosphorylation; phagocytosis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of cell shape; Wnt receptor signaling pathway |
| UniProt Code: | P48729 |
| NCBI GenInfo Identifier: | 31077177 |
| NCBI Gene ID: | 1452 |
| NCBI Accession: | P48729.2 |
| UniProt Secondary Accession: | P48729,Q4JJA0, Q5U046, Q5U047, Q6FGA2, Q71TU5, Q96HD2 Q9UDK3, D3DQG0, D3DQG1, |
| UniProt Related Accession: | P48729 |
| Molecular Weight: | 37,567 Da |
| NCBI Full Name: | Casein kinase I isoform alpha |
| NCBI Synonym Full Names: | casein kinase 1 alpha 1 |
| NCBI Official Symbol: | CSNK1A1 |
| NCBI Official Synonym Symbols: | CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p |
| NCBI Protein Information: | casein kinase I isoform alpha |
| UniProt Protein Name: | Casein kinase I isoform alpha |
| UniProt Synonym Protein Names: | CK1 |
| Protein Family: | Casein kinase |
| UniProt Gene Name: | CSNK1A1 |
| UniProt Entry Name: | KC1A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSNK1A1 antibody (CAB16225) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunohistochemistry of paraffin-embedded human tonsil using CSNK1A1 antibody (CAB16225) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human placenta using CSNK1A1 antibody (CAB16225) at dilution of 1:100 (40x lens). |
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