Cell Biology Antibodies 10

CRHBP Rabbit Polyclonal Antibody (CAB6568)

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SKU:
CAB6568
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CRFBP, CRF-BP, CRHBP
Research Use:
Cell Biology
Frequently bought together:

Description

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CRHBP Antibody (CAB6568)

The CRHBP Antibody (CAB6568) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to CRHBP, researchers can detect and analyze the protein in various cell types, making it an excellent choice for studies in neuroscience, endocrinology, and mental health research.CRHBP, also known as corticotropin-releasing hormone-binding protein, is essential for modulating the effects of stress hormones like corticotropin-releasing hormone (CRH).

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CRHBP Antibody
SKU:CAB6568
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:YLEL REAA DYDP FLLF SANL KREL AGEQ PYRR ALRC LDML SLQG QFTF TADR PQLH CAAF FISE PEEF ITIH YDQV SIDC QGGD FLKV FDGW ILKG EKFP SSQD HPLP SAER YIDF CESG LSRR SIRS SQNV AMIF FRVH EPGN GFTL TIKT DPNL FPCN VISQ TPNG KFTL VVPH QHRN CSFS IIYP VVIK ISDL TLGH VNGL QLKK SSAG CEGI GDFV ELLG GTGL DPSK MTPL ADLC YPFH GPAQ MKVG CDNT VVRM VSSG KHVN RVTF EYRQ LEPY ELEN PNGN SIGE FCLS GL
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:1000 - 1:5000
IHC-P1:100 - 1:500
IF/ICC1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CRFBP, CRF-BP, CRHBP
Positive Sample:Rat brain
Cellular Localization:Secreted.
Calculated MW:36kDa
Observed MW:37kDa

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

Purification MethodAffinity purification
Gene ID1393
RRIDAB_2767162
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat brain, using CRHBP Rabbit pAb (CAB6568) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse kidney tissue using CRHBP Rabbit pAb (CAB6568) at a dilution of 1:300 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of HeLa cells using CRHBP Rabbit pAb (CAB6568). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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