Cell Biology Antibodies 8

COX6B1 Rabbit Polyclonal Antibody (CAB2641)

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SKU:
CAB2641
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
COXG, COX6B, MC4DN7, COXVIb1, COX6B1
Research Use:
Cell Biology
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Description

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COX6B1 Antibody (CAB2641)

The COX6B1 Antibody (CAB2641) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.COX6B1 is a critical component of the mitochondrial respiratory chain, functioning to transfer electrons and generate ATP for cellular energy production. Dysregulation of COX6B1 has been linked to various diseases, including metabolic disorders and neurodegenerative conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:COX6B1 Antibody
SKU:CAB2641
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAED METK IKNY KTAP FDSR FPNQ NQTR NCWQ NYLD FHRC QKAM TAKG GDIS VCEW YQRV YQSL CPTS WVTD WDEQ RAEG TFPG KI
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:COXG, COX6B, MC4DN7, COXVIb1, COX6B1
Positive Sample:A-549, MCF7, Jurkat, HepG2, Mouse brain, Mouse small intestine, Mouse liver, Mouse kidney
Cellular Localization:Mitochondrion Intermembrane Space.
Calculated MW:10kDa
Observed MW:13kDa

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

Purification MethodAffinity purification
Gene ID1340
RRIDAB_2764512
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using COX6B1 Rabbit pAb (CAB2641) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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