Cell Biology Antibodies 11

CKMT2 Rabbit Polyclonal Antibody (CAB8088)

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SKU:
CAB8088
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
SMTCK, CKMT2
Research Use:
Cell Biology
Frequently bought together:

Description

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CKMT2 Antibody (CAB8088)

The CKMT2 Antibody (CAB8088) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been thoroughly validated for use in Western blot applications. By binding specifically to the CKMT2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and metabolism research.CKMT2, also known as mitochondrial creatine kinase, plays a crucial role in maintaining energy balance within cells by facilitating the conversion of ADP to ATP.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CKMT2 Antibody
SKU:CAB8088
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EVRE QPRL FPPS ADYP DLRK HNNC MAEC LTPA IYAK LRNK VTPN GYTL DQCI QTGV DNPG HPFI KTVG MVAG DEES YEVF ADLF DPVI KLRH NGYD PRVM KHTT DLDA SKIT QGQF DEHY VLSS RVRT GRSI RGLS LPPA CTRA ERRE VENV AITA LEGL KGDL AGRY YKLS EMTE QDQQ RLID DHFL FDK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SMTCK, CKMT2
Positive Sample:HeLa, Mouse skeletal muscle, Mouse heart, Mouse diaphragm, Rat skeletal muscle
Cellular Localization:Intermembrane Side, Mitochondrion Inner Membrane, Peripheral Membrane Protein.
Calculated MW:48kDa
Observed MW:40kDa

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Purification MethodAffinity purification
Gene ID1160
RRIDAB_2768935
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CKMT2 Rabbit pAb (CAB8088) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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