Signal Transduction Antibodies 3

CHRNG Rabbit Polyclonal Antibody (CAB7884)

(No reviews yet) Write a Review
SKU:
CAB7884
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
ACHRG, CHRNG
Research Use:
Signal Transduction
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

CHRNG Antibody (CAB7884)

The CHRNG Antibody (CAB7884) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, raised in rabbits, is highly specific for human samples and suitable for use in Western blot applications. By binding to the CHRNG protein, this antibody allows for the detection and analysis of CHRNG expression in various tissues and cell types.The CHRNG gene is essential for neuromuscular transmission and muscle contraction, making it a key target for research into neuromuscular disorders, myasthenia gravis, and other conditions affecting muscle function.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CHRNG Antibody
SKU:CAB7884
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:NVSL RSPH THSM ARGV RKVF LRLL PQLL RMHV RPLA PAAV QDTQ SRLQ NGSS GWSI TTGE EVAL CLPR SELL FQQW QRQG LVAA ALEK LEKG PELG LSQF CGSL KQAA PAIQ ACVE ACNL IACA RHQQ SHFD NGNE EWFL VGRV LDRV CFLA MLSL FICG TAGI FLMA HYNR VPAL PFPG DPRP YLPS PD
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ACHRG, CHRNG
Positive Sample:Mouse skeletal muscle, Rat skeletal muscle
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Postsynaptic Cell Membrane, Synapse.
Calculated MW:58kDa
Observed MW:60kDa

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

Purification MethodAffinity purification
Gene ID1146
RRIDAB_2768913
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CHRNG Rabbit pAb (CAB7884) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
View AllClose

0 Reviews

View AllClose

Related Products