Epigenetics & Nuclear Signaling Antibodies 2
Anti-CHD1 Antibody (CAB15038)
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- SKU:
- CAB15038
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-CHD1 Antibody |
| Antibody SKU: | CAB15038 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1501-1710 of human CHD1 (NP_001261.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1501-1710 of human CHD1 (NP_001261.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IKKR QESQ QNSD QNSN LNPH VIRN PDVE RLKE NTNH DDSS RDSY SSDR HLTQ YHDH HKDR HQGD SYKK SDSR KRPY SSFS NGKD HRDW DHYK QDSR YYSD REKH RKLD DHRS RDHR SNLE GSLK DRSH SDHR SHSD HRLH SDHR SSSE YTHH KSSR DYRY HSDW QMDH RASS SGPR SPLD QRSP YGSR SPFE HSVE HKST PEHT WSSR KT |
| Gene ID: | 1105 |
| Uniprot: | O14646 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 196kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CHD1 |
| Background: | The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. |
| UniProt Protein Function: | CHD-1: a sequence-selective DNA-binding protein. Contains two chromo (chromatin organization modifier) domains and one SNF2-related helicase and ATPase domains. May play an important role in gene regulation. |
| UniProt Protein Details: | Protein type:Helicase; EC 3.6.4.12 Chromosomal Location of Human Ortholog: 5q15-q21 Cellular Component: cytoplasm; nucleus Molecular Function:ATP-dependent DNA helicase activity; protein binding; DNA binding; methylated histone residue binding; ATP binding Biological Process: chromatin remodeling; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; DNA duplex unwinding |
| UniProt Code: | O14646 |
| NCBI GenInfo Identifier: | 269849549 |
| NCBI Gene ID: | |
| NCBI Accession: | O14646.2 |
| Molecular Weight: | 197kDa |
| NCBI Full Name: | Chromodomain-helicase-DNA-binding protein 1 |
| UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 1 |
| UniProt Synonym Protein Names: | ATP-dependent helicase CHD1 |
| Protein Family: | Chromodomain-helicase-DNA-binding protein |
| UniProt Gene Name: | CHD1 |
| UniProt Entry Name: | CHD1_HUMAN |
 | Immunofluorescence analysis of U2OS cells using CHD1 antibody (CAB15038) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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