Anti-CDX2 Antibody (CAB20222)
- SKU:
- CAB20222
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDX2
- Synonyms:
- CDX-3
- Synonyms:
- CDX2/AS
- Synonyms:
- CDX3
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | CDX2 Rabbit mAb |
| Product Code: | CAB20222 |
| Size: | 50uL, 100uL |
| Synonyms: | CDX2, CDX-3, CDX2/AS, CDX3 |
| Applications: | WB, IHC, IF, FC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CDX2. |
| Applications: | WB, IHC, IF, FC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 FC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SW620 |
| Immunogen: | Recombinant protein of human CDX2. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: TBS with 0.05% sodium azide, 0.05% BSA, 40% glycerol, pH7.4. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1045 |
| Uniprot: | Q99626 |
| Cellular Location: | Nucleus |
| Calculated MW: | 40kDa |
| Observed MW: | 38KDa |
| UniProt Protein Function: | CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 13q12.3 Cellular Component: nucleoplasm; nucleus Molecular Function:transcription factor activity Biological Process: anterior/posterior axis specification; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; regulation of somitogenesis; transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q99626 |
| NCBI GenInfo Identifier: | 311033469 |
| NCBI Gene ID: | 1045 |
| NCBI Accession: | Q99626.3 |
| UniProt Secondary Accession: | Q99626,O00503, Q5VTU7, Q969L8, Q9UD92, |
| UniProt Related Accession: | Q99626 |
| Molecular Weight: | 33,520 Da |
| NCBI Full Name: | Homeobox protein CDX-2 |
| NCBI Synonym Full Names: | caudal type homeobox 2 |
| NCBI Official Symbol: | CDX2 |
| NCBI Official Synonym Symbols: | CDX3; CDX-3; CDX2/AS |
| NCBI Protein Information: | homeobox protein CDX-2 |
| UniProt Protein Name: | Homeobox protein CDX-2 |
| UniProt Synonym Protein Names: | CDX-3; Caudal-type homeobox protein 2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | CDX2 |
| UniProt Entry Name: | CDX2_HUMAN |
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