CDX2 Rabbit Monoclonal Antibody (CAB20222)

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SKU:
CAB20222
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
CDX3, CDX-3, CDX2/AS, X2
Research Use:
Epigenetics and Nuclear Signaling
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Description

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CDX2 Monoclonal Antibody (CAB20222)

The CDX2 Monoclonal Antibody (CAB20222) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including immunohistochemistry and Western blotting.CDX2 plays a crucial role in regulating gene expression in the intestinal epithelium, influencing cell proliferation, differentiation, and maintenance of intestinal function.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CDX2 Monoclonal Antibody
SKU:CAB20222
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC3070
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MYVS YLLD KDVS MYPS SVRH SGGL NLAP QNFV SPPQ YPDY GGYH VAAA AAAA ANLD SAQS PGPS WPAA YGAP LRED WNGY APGG AAAA ANAV AHGL NGGS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CDX3, CDX-3, CDX2/AS, X2
Positive Sample:SW620, 293T, Mouse colon
Cellular Localization:Nucleus.
Calculated MW:34kDa
Observed MW:38kDa

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Purification MethodAffinity purification
Gene ID1045
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from SW620 cells, using [KD Validated] CDX2 Rabbit mAb (CAB20222) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of lysates from wild type(WT) and CDX2 knockdown(KD) 293T cells, using [KD Validated] CDX2 Rabbit mAb (CAB20222) at1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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