Epigenetics & Nuclear Signaling Antibodies 5

Anti-CDX2 Antibody (CAB19030)

(No reviews yet) Write a Review
SKU:
CAB19030
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CDX2 Antibody
Antibody SKU:CAB19030
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF IP
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human CDX2
Application:WB IHC IF IP
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SW480, 293T
Immunogen:A synthesized peptide derived from human CDX2
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:1045
Uniprot:Q99626
Cellular Location:Nucleus
Calculated MW:40kDa
Observed MW:38kDa
Anti-CDX2 Antibody (CAB19030)Western blot - CDX2 Rabbit mAb (CAB19030)
Synonyms:CDX2, CDX-3, CDX2/AS, CDX3
Background:This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
UniProt Protein Function:CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 13q12.3

Cellular Component: nucleoplasm; nucleus

Molecular Function:transcription factor activity

Biological Process: anterior/posterior axis specification; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; regulation of somitogenesis; transcription from RNA polymerase II promoter

NCBI Summary:This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
UniProt Code:Q99626
NCBI GenInfo Identifier:311033469
NCBI Gene ID:1045
NCBI Accession:Q99626.3
UniProt Secondary Accession:Q99626,O00503, Q5VTU7, Q969L8, Q9UD92,
UniProt Related Accession:Q99626
Molecular Weight:33,520 Da
NCBI Full Name:Homeobox protein CDX-2
NCBI Synonym Full Names:caudal type homeobox 2
NCBI Official Symbol:CDX2  
NCBI Official Synonym Symbols:CDX3; CDX-3; CDX2/AS  
NCBI Protein Information:homeobox protein CDX-2
UniProt Protein Name:Homeobox protein CDX-2
UniProt Synonym Protein Names:CDX-3; Caudal-type homeobox protein 2
Protein Family:Homeobox protein
UniProt Gene Name:CDX2  
UniProt Entry Name:CDX2_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products

Anti-CDX2 Antibody (CAB20222)

Anti-CDX2 Antibody (CAB20222)

OverviewProduct Name:CDX2 Rabbit mAbProduct Code:CAB20222Size:50uL, 100uLSynonyms:CDX2, CDX-3, CDX2/AS, CDX3Applicatio