Immunology Antibodies 2

CD1D Rabbit Polyclonal Antibody (CAB1760)

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SKU:
CAB1760
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse
Synonyms:
R3, CD1A, R3G1, CD1D
Research Use:
Immunology
Frequently bought together:

Description

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CD1D Antibody (CAB1760)

The CD1D Antibody (CAB1760) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CD1d protein, researchers can effectively detect and analyze its expression in various cell types, making it an essential tool for studies in immunology and autoimmune diseases.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CD1D Antibody
SKU:CAB1760
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EVPQ RLFP LRCL QISS FANS SWTR TDGL AWLG ELQT HSWS NDSD TVRS LKPW SQGT FSDQ QWET LQHI FRVY RSSF TRDV KEFA KMLR LSYP LELQ VSAG CEVH PGNA SNNF FHVA FQGK DILS FQGT SWEP TQEA PLWV NLAI QVLN QDKW TRET VQWL LNGT CPQF VSG
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:R3, CD1A, R3G1, CD1D
Positive Sample:THP-1, Jurkat
Cellular Localization:Cell Membrane, Endosome Membrane, Lysosome Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:38kDa
Observed MW:38kDa/50kDa

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID912
RRIDAB_2763803
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using CD1D Rabbit pAb (CAB1760) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunofluorescence analysis of HeLa cells using CD1D Rabbit pAb (CAB1760). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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