Metabolism Antibodies 1

CBS Rabbit Polyclonal Antibody (CAB1427)

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SKU:
CAB1427
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
Reactivity:
Human, Mouse, Rat
Synonyms:
CBSL, HIP4, CBS
Research Use:
Metabolism
Frequently bought together:

Description

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CBS Antibody (CAB1427)

The CBS Antibody (CAB1427) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and is suitable for use in Western blot applications. By binding to the CBS protein, this antibody allows for the detection and analysis of CBS levels in various cell types, making it ideal for research in fields such as metabolism, biochemistry, and genetic disorders.CBS, also known as cystathionine beta-synthase, plays a pivotal role in maintaining the balance of sulfur-containing amino acids in the body.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CBS Antibody
SKU:CAB1427
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MPSE TPQA EVGP TGCP HRSG PHSA KGSL EKGS PEDK EAKE PLWI RPDA PSRC TWQL GRPA SESP HHHT APAK SPKI LPDI LKKI GDTP MVRI NKIG KKFG LKCE LLAK CEFF NAGG SVKD RISL RMIE DAER DGTL KPGD TIIE PTSG NTGI GLAL AAAV RGYR CIIV MPEK MSSE KVDV LRAL GAEI VRTP TNAR FDSP ESHV GVAW RLKN EIPN SHIL DQYR NASN PLAH YDTT ADEI LQQC DGKL DMLV ASVG TGGT ITGI ARKL KEKC PGCR IIGV DPEG SILA EPEE LNQT EQTT YEVE GIGY DFIP TVLD RTVV DKWF KSND EEAF TFAR MLIA QEGL LCGG SAGS TVAV AVKA AQEL QEGQ RCVV ILPD SVRN YMTK
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CBSL, HIP4, CBS
Positive Sample:HepG2, 293T, HeLa, MCF7, Mouse liver, Rat liver, Rat kidney
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:61kDa
Observed MW:61kDa

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.

Purification MethodAffinity purification
Gene ID875
RRIDAB_2761132
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBS Rabbit pAb (CAB1427) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunofluorescence analysis of paraffin-embedded rat liver using CBS Rabbit pAb (CAB1427) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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