Developmental Biology

CBFA2T3 Rabbit Polyclonal Antibody (CAB14712)

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SKU:
CAB14712
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3, CBFA2T3
Research Use:
Developmental Biology
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Description

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CBFA2T3 Antibody (CAB14712)

The CBFA2T3 Antibody (CAB14712) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.CBFA2T3 plays a crucial role in the regulation of gene expression and cell fate determination, making it a key player in developmental processes and cancer progression. By targeting the CBFA2T3 protein, researchers can investigate its function in various cell types and gain insights into its involvement in hematopoiesis and tumorigenesis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CBFA2T3 Antibody
SKU:CAB14712
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:GQSL QGPT AVVA DPVP GPPE AAHS LGPS LPVG AASP SEAG SAGP SRPG SPSP PGPL DTVP R
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3, CBFA2T3
Positive Sample:Jurkat, Mouse spleen
Cellular Localization:Golgi Apparatus Membrane, Nucleus, Nucleolus, Nucleoplasm.
Calculated MW:71kDa
Observed MW:75kDa

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Purification MethodAffinity purification
Gene ID863
RRIDAB_2761588
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBFA2T3 Rabbit pAb (CAB14712) at 1:900 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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