Cell Biology Antibodies 15

Caveolin-2 Rabbit Monoclonal Antibody (CAB4890)

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SKU:
CAB4890
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
CAV, Caveolin-2
Research Use:
Cell Biology
Frequently bought together:

Description

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Caveolin-2 Monoclonal Antibody (CAB4890)

The Caveolin-2 Monoclonal Antibody (CAB4890) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting Caveolin-2 in a variety of experimental settings.Caveolin-2, a key component of caveolae, plays a crucial role in the regulation of cell signaling pathways and membrane organization. By targeting Caveolin-2, researchers can gain valuable insights into its functions and implications in various biological processes.

This antibody is validated for use in WB, IHC-P, IP, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Caveolin-2 Monoclonal Antibody
SKU:CAB4890
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC0323
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MGLE TEKA DVQL FMDD DSYS HHSG LEYA DPEK FADS DQDR DPHR LNSH LKLG FEDV IAEP VTTH SFDK VWIC SHAL FEIS KYVM YKFL TVFL AIPL AFIA
Tested Applications:WB IHC-P IP ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CAV, Caveolin-2
Positive Sample:HeLa, 293T, Mouse lung
Cellular Localization:Cell Membrane, Cytoplasm, Golgi Apparatus Membrane, Membrane, Nucleus, Peripheral Membrane Protein, Caveola.
Calculated MW:18kDa
Observed MW:21kDa

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).

Purification MethodAffinity purification
Gene ID858
RRIDAB_2863375
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Mouse lung, using Caveolin-2 Rabbit mAb (CAB4890) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageWestern blot analysis of lysates from 293T cells, using Caveolin-2 Rabbit mAb (CAB4890) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunoprecipitation analysis of 300 μg extracts of HeLa cells using 3 μg Caveolin-2 antibody (CAB4890). Western blot was performed from the immunoprecipitate using Caveolin-2 antibody (CAB4890) at a dilution of 1:1000.
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