Epigenetics & Nuclear Signaling Antibodies 1

C10orf2 Rabbit Polyclonal Antibody (CAB13433)

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SKU:
CAB13433
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
PEO, PEO1, SCA8, ATXN8, IOSCA, PEOA3, SANDO, TWINL, MTDPS7, PRLTS5, C10orf2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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C10orf2 Antibody (CAB13433)

The C10orf2 Antibody (CAB13433) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, specifically targets C10orf2 and is highly reactive with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of C10orf2 in various cell types.C10orf2 is a poorly characterized protein with potential implications in various cellular processes, including cell growth, proliferation, and differentiation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.

Product Name:C10orf2 Antibody
SKU:CAB13433
Size:20μL, 100μL
Reactivity:Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:NVLI LQDR KLVT GPGK RYLQ VSKN RFDG DVGV FPLE FNKN SLTF SIPP KNKA RLKK IKDD TGPV AKKP SSGK KGAT TQNS EICS GQAP TPDQ PDTS KRSK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PEO, PEO1, SCA8, ATXN8, IOSCA, PEOA3, SANDO, TWINL, MTDPS7, PRLTS5, C10orf2
Positive Sample:Mouse kidney
Cellular Localization:Mitochondrion Matrix, Mitochondrion Nucleoid.
Calculated MW:77kDa
Observed MW:77kDa

This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Purification MethodAffinity purification
Gene ID56652
RRIDAB_2760295
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from mouse kidney, using C10orf2 Rabbit pAb (CAB13433) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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