Cell Biology Antibodies 11

BBS2 Rabbit Polyclonal Antibody (CAB7425)

(No reviews yet) Write a Review
SKU:
CAB7425
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Mouse, Rat
Synonyms:
BBS, RP74, BBS2
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

BBS2 Antibody (CAB7425)

The BBS2 Antibody (CAB7425) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity for detecting BBS2 in human samples and is suitable for use in Western blot applications.BBS2 plays a crucial role in ciliary function and intracellular trafficking, and mutations in the BBS2 gene can lead to the development of BBS.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:BBS2 Antibody
SKU:CAB7425
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MLLP VFTL KLRH KISP RMVA IGRY DGTH PCLA AATQ TGKV FIHN PHTR NQHV SASR VFQS PLES DVSL LNIN QAVS CLTA GVLN PELG YDAL LVGT
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BBS, RP74, BBS2
Positive Sample:Mouse testis, Mouse liver, Mouse kidney, Rat liver, Rat brain, Rat lung
Cellular Localization:Cell Projection, Cytoplasm, Centriolar Satellite, Centrosome, Cilium Membrane, Cytoskeleton, Microtubule Organizing Center.
Calculated MW:80kDa
Observed MW:100kDa

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.

Purification MethodAffinity purification
Gene ID583
RRIDAB_2767953
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using BBS2 Rabbit pAb (CAB7425) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 5s.
View AllClose

0 Reviews

View AllClose

Related Products