Cell Biology Antibodies 10

ATP2B2 Rabbit Polyclonal Antibody (CAB6875)

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SKU:
CAB6875
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
PMCA2, DFNA82, PMCA2a, PMCA2i, ATP2B2
Research Use:
Cell Biology
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Description

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ATP2B2 Antibody (CAB6875)

The ATP2B2 Antibody (CAB6875) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the ATP2B2 protein, this antibody allows for the detection and analysis of ATP2B2 expression in various cell types, making it ideal for investigations in cell biology and neuroscience.ATP2B2 plays a crucial role in maintaining cellular calcium homeostasis, a key process for proper cell function and signaling.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ATP2B2 Antibody
SKU:CAB6875
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MGDM TNSD FYSK NQRN ESSH GGEF GCTM EELR SLME LRGT EAVV KIKE TYGD TEAI CRRL KTSP VEGL PGTA PDLE KRKQ
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PMCA2, DFNA82, PMCA2a, PMCA2i, ATP2B2
Positive Sample:SH-SY5Y, Mouse ovary, Mouse lung, Mouse liver, Rat liver
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Synapse.
Calculated MW:137kDa
Observed MW:137kDa

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Purification MethodAffinity purification
Gene ID491
RRIDAB_2767435
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from SH-SY5Y cells, using ATP2B2 Rabbit pAb (CAB6875) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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